USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: O00231 USC-OGP 2-DE database:  O00231 O00231 General information about the entry View entry in simple text format Entry name PSD11_HUMAN Primary accession number O00231 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=26S proteasome non-ATPase regulatory subunit 11; AltName: Full=26S proteasome regulatory subunit RPN6; AltName: Full=26S proteasome regulatory subunit S9; AltName: Full=26S proteasome regulatory subunit p44.5;. Gene name Name=PSMD11 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0394: pI=5.94; Mw=45216 Cross-references UniProtKB/Swiss-Prot O00231; PSD11_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PSD11_HUMAN Primary accession number O00231 Secondary accession number(s) A8K3I7 E1P663 O00495 Q53FT5 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 161) Name and origin of the protein Description RecName: Full=26S proteasome non-ATPase regulatory subunit 11; AltName: Full=26S proteasome regulatory subunit RPN6; AltName: Full=26S proteasome regulatory subunit S9; AltName: Full=26S proteasome regulatory subunit p44.5; Gene name Name=PSMD11 Encoded on Name=PSMD11 Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein; Proteasome; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF001212; AAB58732.1; -; mRNA EMBL AB003102; BAA19748.1; -; mRNA EMBL AK290602; BAF83291.1; -; mRNA EMBL AK223196; BAD96916.1; -; mRNA EMBL CH471147; EAW80229.1; -; Genomic_DNA EMBL CH471147; EAW80230.1; -; Genomic_DNA EMBL BC000437; AAH00437.1; -; mRNA EMBL BC004430; AAH04430.1; -; mRNA CCDS CCDS11272.1; -. [O00231-1]; . PIR JC6524; JC6524; . RefSeq NP_001257411.1; NM_001270482.1. [O00231-1]; . RefSeq NP_002806.2; NM_002815.3. [O00231-1]; . UniGene Hs.443379; -; . PDB 5GJQ; EM; 4.50 A; Q=1-422 PDB 5GJR; EM; 3.50 A; 4/Q=1-422 PDB 5L4K; EM; 4.50 A; Q=1-422 PDB 5T0C; EM; 3.80 A; AX/BX=1-422 PDB 5T0G; EM; 4.40 A; X=1-422 PDB 5T0H; EM; 6.80 A; X=1-422 PDB 5T0I; EM; 8.00 A; X=1-422 PDB 5T0J; EM; 8.00 A; X=1-422 PDBsum 5GJQ; -; . PDBsum 5GJR; -; . PDBsum 5L4K; -; . PDBsum 5T0C; -; . PDBsum 5T0G; -; . PDBsum 5T0H; -; . PDBsum 5T0I; -; . PDBsum 5T0J; -; . ProteinModelPortal O00231; -; . SMR O00231; -; . BioGrid 111689; 144; . IntAct O00231; 63; . MINT MINT-1154929; -; . STRING 9606.ENSP00000261712; -; . iPTMnet O00231; -; . PhosphoSitePlus O00231; -; . SwissPalm O00231; -; . BioMuta PSMD11; -; . OGP O00231; -; . EPD O00231; -; . MaxQB O00231; -; . PaxDb O00231; -; . PeptideAtlas O00231; -; . PRIDE O00231; -; . Ensembl ENST00000261712; ENSP00000261712; ENSG00000108671. [O00231-1]; . Ensembl ENST00000457654; ENSP00000393185; ENSG00000108671. [O00231-1]; . GeneID 5717; -; . KEGG hsa:5717; -; . UCSC uc002hhm.5; human. [O00231-1]; . CTD 5717; -; . GeneCards PSMD11; -; . HGNC HGNC:9556; PSMD11; . HPA HPA042275; -; . HPA HPA067433; -; . MIM 604449; gene; . neXtProt NX_O00231; -; . OpenTargets ENSG00000108671; -; . PharmGKB PA33902; -; . eggNOG KOG1463; Eukaryota; . eggNOG COG5159; LUCA; . GeneTree ENSGT00530000063301; -; . HOGENOM HOG000210093; -; . HOVERGEN HBG053738; -; . InParanoid O00231; -; . KO K03036; -; . OMA DCIEWAT; -; . OrthoDB EOG091G0B4C; -; . PhylomeDB O00231; -; . TreeFam TF106230; -; . Reactome R-HSA-1169091; Activation of NF-kappaB in B cells; . Reactome R-HSA-1234176; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; . Reactome R-HSA-1236974; ER-Phagosome pathway; . Reactome R-HSA-1236978; Cross-presentation of soluble exogenous antigens (endosomes); . Reactome R-HSA-174084; Autodegradation of Cdh1 by Cdh1:APC/C; . Reactome R-HSA-174113; SCF-beta-TrCP mediated degradation of Emi1; . Reactome R-HSA-174154; APC/C:Cdc20 mediated degradation of Securin; . Reactome R-HSA-174178; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; . Reactome R-HSA-174184; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; . Reactome R-HSA-180534; Vpu mediated degradation of CD4; . Reactome R-HSA-180585; Vif-mediated degradation of APOBEC3G; . Reactome R-HSA-187577; SCF(Skp2)-mediated degradation of p27/p21; . Reactome R-HSA-195253; Degradation of beta-catenin by the destruction complex; . Reactome R-HSA-202424; Downstream TCR signaling; . Reactome R-HSA-211733; Regulation of activated PAK-2p34 by proteasome mediated degradation; . Reactome R-HSA-2467813; Separation of Sister Chromatids; . Reactome R-HSA-2871837; FCERI mediated NF-kB activation; . Reactome R-HSA-349425; Autodegradation of the E3 ubiquitin ligase COP1; . Reactome R-HSA-350562; Regulation of ornithine decarboxylase (ODC); . Reactome R-HSA-382556; ABC-family proteins mediated transport; . Reactome R-HSA-450408; AUF1 (hnRNP D0) binds and destabilizes mRNA; . Reactome R-HSA-4608870; Asymmetric localization of PCP proteins; . Reactome R-HSA-4641257; Degradation of AXIN; . Reactome R-HSA-4641258; Degradation of DVL; . Reactome R-HSA-5358346; Hedgehog ligand biogenesis; . Reactome R-HSA-5362768; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; . Reactome R-HSA-5607761; Dectin-1 mediated noncanonical NF-kB signaling; . Reactome R-HSA-5607764; CLEC7A (Dectin-1) signaling; . Reactome R-HSA-5610780; Degradation of GLI1 by the proteasome; . Reactome R-HSA-5610783; Degradation of GLI2 by the proteasome; . Reactome R-HSA-5610785; GLI3 is processed to GLI3R by the proteasome; . Reactome R-HSA-5632684; Hedgehog 'on' state; . Reactome R-HSA-5658442; Regulation of RAS by GAPs; . Reactome R-HSA-5668541; TNFR2 non-canonical NF-kB pathway; . Reactome R-HSA-5676590; NIK-->noncanonical NF-kB signaling; . Reactome R-HSA-5678895; Defective CFTR causes cystic fibrosis; . Reactome R-HSA-5687128; MAPK6/MAPK4 signaling; . Reactome R-HSA-5689603; UCH proteinases; . Reactome R-HSA-5689880; Ub-specific processing proteases; . Reactome R-HSA-6798695; Neutrophil degranulation; . Reactome R-HSA-68827; CDT1 association with the CDC6:ORC:origin complex; . Reactome R-HSA-68949; Orc1 removal from chromatin; . Reactome R-HSA-69017; CDK-mediated phosphorylation and removal of Cdc6; . Reactome R-HSA-69229; Ubiquitin-dependent degradation of Cyclin D1; . Reactome R-HSA-69481; G2/M Checkpoints; . Reactome R-HSA-69601; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; . Reactome R-HSA-8852276; The role of GTSE1 in G2/M progression after G2 checkpoint; . Reactome R-HSA-8854050; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; . Reactome R-HSA-983168; Antigen processing: Ubiquitination & Proteasome degradation; . ChiTaRS PSMD11; human; . GeneWiki PSMD11; -; . GenomeRNAi 5717; -; . PRO PR:O00231; -; . Proteomes UP000005640; Chromosome 17; . Bgee ENSG00000108671; -; . CleanEx HS_PSMD11; -; . ExpressionAtlas O00231; baseline and differential; . Genevisible O00231; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:1904813; C:ficolin-1-rich granule lumen; TAS:Reactome; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0022624; C:proteasome accessory complex; IDA:UniProtKB; . GO GO:0000502; C:proteasome complex; IDA:UniProtKB; . GO GO:0008541; C:proteasome regulatory particle; lid subcomplex; IBA:GO_Central GO GO:0034774; C:secretory granule lumen; TAS:Reactome; . GO GO:0005198; F:structural molecule activity; IBA:GO_Central; . GO GO:0031145; P:anaphase-promoting complex-dependent catabolic process; TAS:Reactome; . GO GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAP-dependent; TAS:Reactome GO GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome; . GO GO:0000165; P:MAPK cascade; TAS:Reactome; . GO GO:0090090; P:negative regulation of canonical Wnt signaling pathway; TAS:Reactome; . GO GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; TAS:Reactome; . GO GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0038061; P:NIK/NF-kappaB signaling; TAS:Reactome; . GO GO:0090263; P:positive regulation of canonical Wnt signaling pathway; TAS:Reactome; . GO GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; TAS:Reactome; . GO GO:0043248; P:proteasome assembly; IMP:UniProtKB; . GO GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; TAS:Reactome; . GO GO:0016579; P:protein deubiquitination; TAS:Reactome; . GO GO:0000209; P:protein polyubiquitination; TAS:Reactome; . GO GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome; . GO GO:0043488; P:regulation of mRNA stability; TAS:Reactome; . GO GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome; . GO GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome; . GO GO:0048863; P:stem cell differentiation; IMP:UniProtKB; . GO GO:0002223; P:stimulatory C-type lectin receptor signaling pathway; TAS:Reactome; . GO GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome; . GO GO:0055085; P:transmembrane transport; TAS:Reactome; . GO GO:0033209; P:tumor necrosis factor-mediated signaling pathway; TAS:Reactome; . GO GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB; . GO GO:0060071; P:Wnt signaling pathway; planar cell polarity pathway; TAS:Reactome Gene3D 1.10.10.10; -; 1; . Gene3D 1.25.40.10; -; 1; . InterPro IPR000717; PCI_dom; . InterPro IPR011990; TPR-like_helical_dom; . InterPro IPR011991; WHTH_DNA-bd_dom; . Pfam PF01399; PCI; 1; . SMART SM00088; PINT; 1; . SUPFAM SSF46785; SSF46785; 1; . SUPFAM SSF48452; SSF48452; 1; .

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